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Ryo Kobayashi Selected Research

polaprezinc (Z 103)

1/2021Polaprezinc for prevention of oral mucositis in patients receiving chemotherapy followed by hematopoietic stem cell transplantation: A multi-institutional randomized controlled trial.
8/2018Prophylactic Effect of Polaprezinc, a Zinc-L-carnosine, Against Chemotherapy-induced Oral Mucositis in Pediatric Patients Undergoing Autologous Stem Cell Transplantation.
8/2016Preparation and clinical evaluation of a novel lozenge containing polaprezinc, a zinc-L-carnosine, for prevention of oral mucositis in patients with hematological cancer who received high-dose chemotherapy.
1/2016Effect of polaprezinc on oral mucositis, irradiation period, and time to discharge in patients with head and neck cancer.
12/2014Polaprezinc prevents oral mucositis in patients treated with high-dose chemotherapy followed by hematopoietic stem cell transplantation.

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Ryo Kobayashi Research Topics

Disease

15Neoplasms (Cancer)
06/2022 - 04/2008
7Nausea
06/2022 - 01/2014
7Vomiting
06/2022 - 01/2014
6Infections
09/2022 - 01/2011
6Stomatitis
01/2021 - 01/2014
5Pain (Aches)
03/2022 - 12/2014
5Colorectal Neoplasms (Colorectal Cancer)
08/2021 - 06/2016
3Pancreatic Neoplasms (Pancreatic Cancer)
08/2021 - 11/2018
3Neoplasm Metastasis (Metastasis)
05/2021 - 09/2011
3Stomach Neoplasms (Stomach Cancer)
05/2021 - 12/2017
3Head and Neck Neoplasms (Head and Neck Cancer)
01/2016 - 04/2008
2Cachexia
04/2022 - 12/2020
2Peripheral Nervous System Diseases (PNS Diseases)
03/2022 - 08/2021
2Breast Neoplasms (Breast Cancer)
05/2021 - 01/2018
2Adenocarcinoma
05/2021 - 09/2011
2Neutropenia
11/2018 - 01/2014
2Hematologic Neoplasms (Hematological Malignancy)
08/2018 - 12/2014
2Constipation
01/2017 - 01/2014
2Anaphylaxis (Anaphylactic Shock)
01/2012 - 10/2010
2Appendicitis
11/2011 - 02/2010
1COVID-19
09/2022
1Human Influenza (Influenza)
07/2022
1Uterine Cervical Neoplasms (Cancer of the Cervix)
06/2022
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2022
1Fistula
02/2022
1Empyema
02/2022
1Cellulitis
01/2022
1Glycogen Storage Disease (Glycogenosis)
01/2022
1Anorexia
08/2021
1Chronic Renal Insufficiency
08/2021
1Hyperammonemia
08/2021
1Lymphatic Metastasis
05/2021
1Ovarian Neoplasms (Ovarian Cancer)
05/2021
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
03/2021
1Febrile Neutropenia
03/2021
1Critical Illness (Critically Ill)
01/2021
1Periodontal Diseases (Periodontal Disease)
04/2020

Drug/Important Bio-Agent (IBA)

5AntiemeticsIBA
06/2022 - 12/2016
5polaprezinc (Z 103)IBA
01/2021 - 12/2014
4Pharmaceutical PreparationsIBA
03/2022 - 12/2015
4SuspensionsIBA
08/2018 - 12/2014
4AlginatesIBA
08/2018 - 12/2014
3AntigensIBA
01/2018 - 10/2010
2Cisplatin (Platino)FDA LinkGeneric
06/2022 - 12/2017
2BilirubinIBA
07/2021 - 11/2018
2Oxaliplatin (Eloxatin)FDA LinkGeneric
11/2018 - 12/2016
2Irinotecan (Camptosar)FDA LinkGeneric
11/2018 - 12/2016
2azuleneIBA
08/2018 - 12/2014
2Olanzapine (Zyprexa)FDA Link
01/2018 - 12/2017
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2018 - 01/2017
2AntibodiesIBA
01/2018 - 01/2011
2EmeticsIBA
12/2017 - 12/2016
2Immunoglobulin E (IgE)IBA
01/2012 - 10/2010
2Biological ProductsIBA
09/2011 - 04/2008
1Immunoglobulin M (IgM)IBA
09/2022
1Indicators and Reagents (Reagents)IBA
09/2022
1Immunoglobulin G (IgG)IBA
09/2022
1Neutralizing AntibodiesIBA
09/2022
1SilverIBA
07/2022
1Neurokinin-1 Receptor AntagonistsIBA
06/2022
1Dexamethasone (Maxidex)FDA LinkGeneric
06/2022
1Serotonin (5 Hydroxytryptamine)IBA
06/2022
1pembrolizumabIBA
04/2022
1Antineoplastic Agents (Antineoplastics)IBA
04/2022
1Branched-Chain Amino AcidsIBA
08/2021
1130-nm albumin-bound paclitaxelIBA
07/2021
1AlbuminsIBA
07/2021
1GemcitabineFDA Link
07/2021
1regorafenibIBA
07/2021
1IfosfamideFDA LinkGeneric
06/2021
1Letrozole (Femara)FDA LinkGeneric
05/2021
1Estrogens (Estrogen)FDA Link
05/2021
1Hormones (Hormone)IBA
05/2021
1Estrogen ReceptorsIBA
05/2021
1pegfilgrastim (Neulasta)FDA Link
03/2021
1amrubicinIBA
03/2021
1Syndecan-1 (Syndecan 1)IBA
01/2021
12-methacryloyloxyethyl phosphorylcholineIBA
01/2021
1Biomarkers (Surrogate Marker)IBA
01/2021
1afliberceptIBA
01/2021
1Bevacizumab (Avastin)FDA Link
01/2021
1PolymersIBA
01/2021
1NivolumabIBA
12/2020
1Glycated Hemoglobin (Glycosylated Hemoglobin)IBA
04/2020
1Sunitinib (Sutent)FDA Link
11/2019

Therapy/Procedure

17Drug Therapy (Chemotherapy)
04/2022 - 12/2014
11Therapeutics
06/2022 - 02/2010
5Radiotherapy
06/2022 - 12/2014
4Hematopoietic Stem Cell Transplantation
01/2021 - 12/2014
2Length of Stay
07/2018 - 01/2014
1Thoracostomy
02/2022
1Negative-Pressure Wound Therapy
02/2022
1Sutures (Suture)
02/2022
1Gastrostomy
01/2022
1Combination Drug Therapy (Combination Chemotherapy)
07/2021
1Decompression
05/2021
1Laparotomy
05/2021
1Catheters
01/2021
1Transplantation
01/2021
1Duration of Therapy
04/2020